Immune response toH pylori

Immune Response to Helicobacter pylori

Local Immune Response in Helicobacter pylori Infection

There have been few studies concerning the cytokine profiles in gastric mucosa of Helicobacter pylori-infected patients with normal mucosa, chronic gastritis, and gastric carcinoma (GAC).In the present study, we aimed to elucidate the genomic expression levels and immune pathological roles of cytokines-interferon (IFN)-γ, tumor necrosis factor (TNF)-α, interleukin (IL)-4, IL-6, IL-10, transform...

The Immune Response to Helicobacter pylori

The immune response to Helicobacter pylori involves different mechanisms that are both protective and damaging to the host. The innate and the adaptive immune responses lead to inflammatory as well as anti-inflammatory responses, allowing for persistence of many infections. Thus, developing new therapeutics and effective vaccines against H. pylori has proven to be arduous. Despite many immunisa...

Could Helicobacter pylori cause an abnormal immune response?

Genel Sur1, Lucia Sur2, Anamaria Girbovan3, Gabriel Samasca4, Giulia Alexandru5, Rahela Carpa5, Iulia Lupan6 1Department of Pediatrics II, Iuliu Hatieganu University of Medicine, Romania 2 Department of Pediatrics I, Iuliu Hatieganu University of Medicine, Romania 3 Department of Immunology II, Iuliu Hatieganu University of Medicine, Romania 4 Emergency Hospital for Children, Romania 5 Departme...

Lymphoid follicles in antral mucosa: immune response to Campylobacter pylori?

The prevalence of lymphoid follicles in endoscopic biopsy specimens from normal antral mucosa (n = 220), mucosa with reflux gastritis (n = 104), and in cases with Campylobacter pylori-associated gastritis (n = 2544) was studied. In the latter group whether there were associations between degree and activity of gastritis and the prevalence of lymphoid follicles and between the occurrence of lymp...